Cardiovascular Events in Systemic Lupus Erythematosus: A Nationwide Study in Spain From the RELESSER Registry.

6 , 7 Measurements of the incidence and prevalence of cardiovascular (CV) events may fluctuate because of differences between studies (eg, sample size, different populations, design, or inadequate adjustment for potential confounding factors); a decreasing trend in the risk might even be occurring. 6 – 9 This trend may be related to a better control of lupus activity and other SLE-associated risk factors for atherosclerosis such as glucocorticoids, oxidative stress, adipokines, and others. 10 The risk of CV events in SLE is difficult to study given that despite the increased relative risk of CV events in this population, the absolute number of events per year in any given cohort is relatively small.

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