Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer.

BMC Cancer · 2015 · PMC4603342 · PMID 26459286

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highly significantno p-value reported

Furthermore, the addition of 15 μM of resveratrol and 5 μM of pterostilbene exhibited highly significant inhibitory effects when compared with single doses and combinatorial treatments at 24 h.

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