With respect to the relationship between TFPI-2 expression and LNM in malignant tumors, Zhang et al 33 suggested that TFPI-2 expression has a decreasing trend and is significantly correlated with LNM in the progression of cervical cancer.
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Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
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