Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.

Genes Dev · 2015 · PMC4604347 · PMID 26443850

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highly significantno p-value reported

We found that Esc2 associates with 67.4% of early ARS regions that fire under our experimental conditions, with the enrichment of Esc2 at early ARS regions being statistically highly significant ( P -value of 1.1 × 10 −6 ).

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