highly significantp = 0.0003
However, the OR associated with INSTI use is highly significant [7.67 (2.54–23.2), p = 0.0003] and a larger population would have most probably affected the CI95% of the OR but not the direction of the association even if we cannot definitively rule-out the possibility of an allocation bias secondary to a small selected subgroup of patients receiving raltegravir.