Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans.

We found a highly significant and large effect of the nucleotides at position −3 and at position −2 on translation efficiency (Bonferroni adjusted Kruskal–Wallis test P = 5.7 × 10 −20 for position −3; P = 1.2 × 10 −17 at position −2) ( Fig. 5 A; Supplemental Fig.

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