A pilot cohort study of cerebral autoregulation and 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy who received therapeutic hypothermia.

(None of the neonates had unilateral intracranial lesions on follow-up MRI.) We identified the MAP OPT in each time period (hypothermia, rewarming, first 6 h of normothermia) as the bin that had the most negative HVx when the bar graph exhibited an overall trend of increasing HVx values as MAP deviated from this nadir (Fig. 1a and b ).

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