At the time of functional recovery (P23), H/I + metformin pups displayed significant increases in YFP-positive cells in the olfactory bulb and subventricular zone and an increasing trend in the hippocampus where NPCs and ongoing neurogenesis are normally observed ( Figures S2 G–S2K).
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Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury.
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