highly significantP < 1 × 10 −10
At least one error affecting a whole chromosome was detected for total of 15,842 (62.1%) of the remaining 25,497 blastomeres as compared to 7,623 (44.3%) of 17,219 TE biopsies, a highly significant difference [ χ 2 (1, N = 42,716) = 1323.8, P < 1 × 10 −10 ].