Antigen-induced arthritis in rats is associated with increased growth-associated protein 43-positive intraepidermal nerve fibres remote from the joint.

Arthritis Res Ther · 2015 · PMC4621858 · PMID 26503622

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highly significantp < 0.0001actually significant

Intra- and interobserver agreements for the counts of IENFs were highly significant, as verified by correlations (intraobserver reliability for paw pad skin tested on two counts each for ten randomly chosen slides: R = 0.9879, p < 0.0001; interobserver reliability for paw pad skin tested on one count by two observers for ten randomly chosen slides: R = 0.8303, p = 0.0047).

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