For this reason, and to prevent an overfitting of the model, only these two established prognostic factors were introduced in different multivariate Cox hazard regression models, along with the immunohistochemical parameters which resulted significant/borderline significant in the univariate analyses – i.e.
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Prognostic value of inhibitors of apoptosis proteins (IAPs) and caspases in prostate cancer: caspase-3 forms and XIAP predict biochemical progression after radical prostatectomy.
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