The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues.

Epigenetics · 2015 · PMC4622544 · PMID 25634226

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highly significantP -value = 1.2 × 10 −15actually significant

We found, for H3K4me1, a highly significant enrichment for blood u-tDMRs (mean: 9.7; P -value = 1.2 × 10 −15 t-test) and liver f-tDMRs (mean: 9.3; P -value <2.2 × 10 −16 ; t-test for regions with methylation difference <0).

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