Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia.

While no pathways were identified as over-represented in the HeH and dic(9;20) subtypes, a highly significant association ( P = 5.7 × 10 −17 , after correction) was found with neuroactive ligand-receptor interaction in the TCF3-PBX1 subtype (online supplementary Table 2 ).

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