Determination of potential role of antioxidative status and circulating biochemical markers in the pathogenesis of ethambutol induced toxic optic neuropathy among diabetic and non-diabetic patients.

A decreasing trend of high-density lipoprotein levels was recorded (control = 1.73 mg/dl; non-diabetic = 1.27 mg/dl and diabetic = 1.17 mg/dl), however a reverse trend was found for total cholesterol (control = 4.44 mg/dl; non-diabetic = 4.91 mg/dl and diabetic = 6.37 mg/dl), and low-density lipoprotein (control = 2.31 mg/dl; non-diabetic = 2.83 mg/dl and diabetic = 3.05 mg/dl) blood levels.

also in 47,180 other papers

Data regarding hematological (RBC, p value = 0.02; Hemoglobin, p value = 0.02), hepatic (total bilirubin, p value = 0.01), renal (urea, p value = 0.03; creatinine, p value = 0.007), lipid (total cholesterol, p value = 0.01; total triglycerides, p value = 0.03) and antioxidative (superoxide dismutase, p value = 0.005; glutathione, p value = 0.02; catalase, p value = 0.02) profile showed a highly significant difference among the studied groups specially patients with diabetes.

also in 132,142 other papers