Macrolactone Nuiapolide, Isolated from a Hawaiian Marine Cyanobacterium, Exhibits Anti-Chemotactic Activity.

Evaluation of Fractionated Extracts for Anti-Chemotactic Behavior Sample well 13-F10, an extract from a cyanobacterium whose partial 16S gene sequence showed a highly significant hit to Okeania plumata , was selected for further evaluation because it showed chemotaxis inhibition activity at lower dosage (10 μg/mL), and it did not show cytotoxicity at these concentrations ( Figure S1 ).

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