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Does analgesic overuse matter? Response to OnabotulinumtoxinA in patients with chronic migraine with or without medication overuse.

Springerplus · 2015 · PMC4628076 · PMID 26543724

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However, there was weak evidence that the reduction was greater in patients without medication overuse, although this result was not quite statistically significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.