3 The idea that sex steroids are involved in MS and that they might be a therapeutic option also originates from retrospective studies revealing that pregnancy has a favorable trend for the course of MS on a short- and long-term basis. 4 Remission of symptoms is seen during pregnancy, in particular during the last trimester when estrogens and progesterone plasma levels are at their maximum. 5 Postpartum, MS symptoms exacerbate again. 4 Recent reports, however, have shown that
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Progesterone Enhanced Remyelination in the Mouse Corpus Callosum after Cuprizone Induced Demyelination.
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