AmpliconDuo: A Split-Sample Filtering Protocol for High-Throughput Amplicon Sequencing of Microbial Communities.

At the rare end in the lower left of the plot, even small absolute deviations show up as large distances from the diagonal, while at the high read count end in the upper right much larger absolute deviations that might be significant (red points) at the chosen false discovery rate shrink to only small apparent distances from the diagonal.

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