The role of p19 in cancer and metastasis processes It may be significant that H-Ras is regulated by miRNAs, such as the let-7 miRNA family [ 27 , 29 ], and that the alternative splicing of H-Ras, which favors p19 over p21, has consequences as regards the levels of certain miRNAs (Fig. 1a and Additional file 1 ).
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The role of p19 and p21 H-Ras proteins and mutants in miRNA expression in cancer and a Costello syndrome cell model.
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