SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression.

Oncogenesis · 2015 · PMC4632074 · PMID 26258891

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Interestingly, we found four enriched pathways, namely mineral absorption, adrenergic signaling in cardiomyocytes, salivary secretion and legionellosis to be highly significant in shSPINK1 group as compared with shSCRM cells ( Figure 4c ).

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