highly significantP <2.664e −10
A highly significant ( P <2.664e −10 , two-sample test for equality of proportions) negative correlation ( R =−0.87, Pearson's product–momentum correlation) between Esrp2 KO and overexpression results indicates that developmentally regulated splicing of a subset of pre-mRNAs is extremely sensitive to ESRP2 levels ( Fig. 6f ).