Gender effects Within the entire “control plus AD” cohort, there was an obvious trend for higher OCRs in women relative to men (Figure 2A ) and there was in fact a significantly higher level of the maximum capacity OCR parameter in women.
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Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients.
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The sentences
In addition to the significant effect on maximum capacity, there was an apparent trend for higher levels of the other four OCR parameters in women.