Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation.

BMC Cancer · 2015 · PMC4641423 · PMID 26555773

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closest p · 0.0× alpha

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The sentences

highly significantp = 1.28E-05actually significant

In SW-1353 cells a highly significant down-regulation by 100 μM diacerein in the expression of cyclin B1 to 0.095 ± 0.03 ( p = 1.28E-05), CDK1 levels to 0.154 ± 0.02 ( p = 9.82E-06), and the CDK2 levels to 0.443 ± 0.12 ( p = 0.002) could be demonstrated.

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