Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

Oncogene · 2016 · PMC4650263 · PMID 26257057

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

Consistent with a broad Wnt-dependent signaling network, CRCs with gain of function RSPO mutations respond to ETC-159 treatment with a rapid and marked shift in the transcriptome including a highly significant decrease in proliferation and stem cell markers, and an increase in differentiation genes.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.