As expected, MPTP caused a highly significant death-rate among TH-positive neurons in the SNpc, with around 50% of these neurons lost ( Fig. 3 A and B).
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Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
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