Influence of glucocorticoid receptor gene NR3C1 646 C>G polymorphism on glucocorticoid resistance in asthmatics: a preliminary study.

Cent Eur J Immunol · 2015 · PMC4655382 · PMID 26648776

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highly significantno p-value reported

Significantly higher percentages of FEV 1 were observed among GCs sensitive asthmatic patients after prednisolone therapy, as compared to GCs resistant asthmatic patients ( Table 1 ). There was a highly significant difference in frequencies of NR3C1 646 C>G genotypes and alleles between asthmatic patients and controls.

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