Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival.

Neoplasia · 2015 · PMC4656807 · PMID 26585234

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highly significantno p-value reported

Although the levels of mRNA were much lower in the OVCA420 and OVCAR3 cells, the fold induction was highly significant, and these cells exhibited more dramatic cell apoptosis than the ALST or OVCA433 cells in response to the exogenous p53.

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