SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair.

Oncogene · 2015 · PMC4660036 · PMID 25728682

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highly significantP =3.8e-14actually significant

A highly significant correlation was observed between SETD2 and H3K36me3 immunohistochemical staining ( P =3.8e-14, Cochran-Armitage test, Supplementary Figure S3a ), suggesting that absence of H3K36me3 staining is a good surrogate for SETD2 loss-of-function. 8 DNA damage was assessed by staining for phosphorylated his

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