We also repeated the inverse analysis, identifying the most parsimonious list of SNPs that produced a cumulative posterior probability of ≥0.95 of the splicing QTL association and found the cumulative posterior probability of the GWAS association from the GAME-ON data ( Supplementary Material, Table S9 ). For some of the loci, such as STXBP4, SRGAP2D and RAD51L1 , the breast cancer association is highly significant and thus the number of likely SNPs is relatively small.
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Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.
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