Modulation of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immunity in a HMGB1-, nucleotide- and T-cell-dependent manner.

Cell Death Dis · 2015 · PMC4669707 · PMID 25973681

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highly significantno p-value reported

In vivo , again, only combination of the multimodal treatment with zVAD-fmk and not only RT with zVAD-fmk resulted in highly significant tumor growth retardation ( Figure 5 ).

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