Collagen fragment biomarkers as serological biomarkers of lean body mass - a biomarker pilot study from the DAHANCA25B cohort and matched controls.

We found no significant differences between the intervention group and the control group for IC6 and ProC3, nor for the ratio between IC6 and C6M, whereas for C6M, a highly significant difference ( P < 0.001) was observed ( Figure 1 ).

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Biomarker levels across times In the two-way mixed models analysis, significant main effects for time and borderline significant group effects could be observed for the IC6 biomarker (time: P = 0.0161; group: P = 0.0569) and the IC6/C6M ratio (time: P = 0.0282; group: P = 0.0503).

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