Atrial fibrillation in heart failure: what should we do?

There was a small and marginally significant improvement in LVEF with combination β-blocker/digoxin compared with placebo/digoxin after 4 months of treatment (30.6 ± 9.6% vs. 26.0 ± 12.4%; P = 0.048). 56 Calcium channel blockers Non-dihydropyridine calcium channel blockers (verapamil or diltiazem) are not recommended in patients with signific

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In patients with AF the HR was 0.97 (95% CI 0.83–1.14), with the interaction P -value for baseline rhythm highly significant at 0.002 with no heterogeneity (see Figure 4 ). 14 The lack of benefit in AF was consistent across all sub-groups, including age categories, gender, NYHA class, and baseline heart rate.

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