Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage.

Sci Rep · 2015 · PMC4671025 · PMID 26639318

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a decreasing trendP < 0.1so close (0.05 < p ≤ 0.1)

Compared with` the control, the mRNA expression of Aggrecan and Col2α1 , which are genes that reflect cartilage function, were significantly decreased (P < 0.01) or exhibited a decreasing trend ( P < 0.1).

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