Accentuating and Opposing Factors Leading to Development of Thoracic Aortic Aneurysms Not Due to Genetic or Inherited Conditions.

Front Cardiovasc Med · 2015 · PMC4671360 · PMID 26664893

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highly significantno p-value reported

A recent meta-analysis showed that there was a highly significant reduction in TIMP-1 and TIMP-2 in TAA compared to controls without TAA, resulting in a MMP-9 to TIMP-1 or TIMP-2 ratio over 3.5-fold greater than controls ( 40 ).

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