Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice.

Nutr Metab (Lond) · 2015 · PMC4672495 · PMID 26649066

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a trend towards significanceno p-value reported

This is consistent with the reduced fat excretion and the increase in CD36/FAT gene expression in the HFD + Lac, which only reached a trend towards significance from HFD.

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