High-throughput transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium abscessus Smooth and Rough variants.

Seventy three of the core response genes to MAB were also identified as part of the core response to MTB (Additional file 6 : Table S3), representing a highly significant overlap ( P < 5.482e-24, hypergeometric test) and suggesting a conserved role for type-I IFN responses across diverse mycobacterial species.

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