Protein Kinase C-Independent Inhibition of Organic Cation Transporter 1 Activity by the Bisindolylmaleimide Ro 31-8220.

When a more stringent cut-off value of |r| > 0.9 was applied, 13 molecular descriptors were found to be correlated with OCT1 activity inhibition ( Table 2 ); linear regression analysis indicated a highly significant positive linear relation between the index values of these descriptors and the % of OCT1 activity inhibition ( S5 Fig ).

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