Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(-/-) Mouse Model of Preeclampsia/Fetal Growth Restriction.

Sci Rep · 2015 · PMC4678899 · PMID 26667607

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may be significantno p-value reported

Given the increased concentration of sphingolipids observed in COMT −/− mice compared with controls, it appears there may be significant alterations in lipid metabolism pathways, which could result in an increased production of ceramides.

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