British Society of Gastroenterology/Association of Coloproctologists of Great Britain and Ireland guidelines for the management of large non-pedunculated colorectal polyps.

A large analysis of T1 colorectal carcinomas in 2002 (n=7543) found that lesions with deep submucosal invasion (sm3) were associated with a highly significant risk of lymph node metastases (p<0.001). 64 This histological information is therefore vital in establishing whether a patient has been cured, the risk of recurrence and planning of subsequent treatment.

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