Efficacy and tolerability studies evaluating a sleep aid and analgesic combination of naproxen sodium and diphenhydramine in the dental impaction pain model in subjects with induced transient insomnia.

Int J Clin Pract · 2015 · PMC4682450 · PMID 25996289

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failed to reach significanceno p-value reported

In the second study, the combination product (NS 440 mg/DPH 25 mg) failed to reach significance for either co-primary end-point against the individual ingredients alone.

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