Mechanisms of hyoscine butylbromide to improve adenoma detection: A case-control study of surface visualization at simulated colonoscope withdrawal.

Probability values were considered significant at the 5 % level and P values ≥ 0.05 but < 0.1 were considered to indicate a statistical trend.

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Similarly there were significant reductions or there was a trend toward significance for reduction in total missed areas and intermediate (300 – 1000 mm 2 ) sized missed areas between the no-antispasmodic group and both the 20-mg and 40-mg groups, but not between the 20-mg and 40-mg groups ( Table 2 ).

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When antispasmodic was used, there was a highly significant relative increase in the total colonic surface visualized (2.6 and 3.9 % for prone and supine datasets, respectively), equivalent to relative reductions in percentage surface unseen of 18 % and 25 % ( Table 1 ).

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