Metabolomic and Gene Expression Profiles Exhibit Modular Genetic and Dietary Structure Linking Metabolic Syndrome Phenotypes in Drosophila.

Using this approach in previous studies, we observed highly significant genetic, dietary, and genotype-by-diet variation for each of the gross phenotypes of weight, total sugar, and triglycerides (Supporting Information, Figure S1 ) ( Reed et al. 2010 , 2014 ).

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