Barely Significant
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Scaling Chromosomes for an Evolutionary Karyotype: A Chromosomal Tradeoff between Size and Number across Woody Species.

PLoS One · 2015 · PMC4684206 · PMID 26657837

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may be significantno p-value reported
The tradeoff may be significant as an evolved mechanism that prevents the over-asymmetry of a karyotype for the sake of the maintenance of chromosome diversity, and it may also be a biomechanical limit of spindle fibers.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.