Expression of hypoxia-inducible factor-1alpha and cell cycle proteins in invasive breast cancer are estrogen receptor related.

Breast Cancer Res · 2004 · PMC468666 · PMID 15217513

Europe PMC DOI

hedged sentences

0.1050

closest p · 2.1× alpha

0.1050

boldest claim

The sentences

a positive trendP = 0.105not close (p > 0.1)

A positive trend between high concentrations of HIF-1α and expression of p21 ( P = 0.105) was noticed, and there was a significant inverse association between Bcl-2 ( P = 0.025) and HIF-1α expression.

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almost significantno p-value reported

Little is known about the interaction between HIF-1 and ER, but an almost significant positive association was found in endometrial cancer [ 30 ] but not in breast cancer [ 11 , 31 ].

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