Barely Significant
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Effect of Atlas Vertebrae Realignment in Subjects with Migraine: An Observational Pilot Study.

Biomed Res Int · 2015 · PMC4689902 · PMID 26783523

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an increasing trendno p-value reported
Subject 01 displayed an increasing trend in ICCI from 5.02 at baseline to 6.69 at week 24, whereas at week 8, results were interpreted as consistent or remaining the same.

also in 63,971 other papers

a decreasing trendno p-value reported
Subject 02 demonstrated a decreasing trend in ICCI from baseline of 15.17 to 9.47 at week 24.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.