Epigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug Response.

Genome-scale analysis of eight matUPD7 patients, a segmental matUPD7q31-qter, a rare patUPD7 case and 10 controls on the Infinium Human Methylation 450K BeadChip with 30,017 CpG methylation probes for chromosome 7 showed highly significant clustering of DMRs only on chromosome 7, including the known imprinted loci growth factor receptor bound protein 10 ( GRB10 ), sarcoglycan epsilon/paternally expressed 10 ( SGCE/PEG10 ), and mesoderm specific transcript ( PEG/MEST ).

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