Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models.

In normoxic conditions the inhibitory effect of all 5 compounds on cell proliferation in this cell line was highly significant ( P < 0.001) at 30 and 100 μM except for FC9396A which was significant at 100 μM alone and for FC9403 which significantly inhibited cell proliferation at 10 μM (Figure 1B ).

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