The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice.

Oncotarget · 2015 · PMC4695113 · PMID 26061745

Europe PMC DOI

hedged sentences

0.0410

closest p · 0.8× alpha

0.0590

boldest claim

The sentences

marginally significantp = 0.041actually significant

The levels of protein carbonyls had a marginally significant negative association to the mass of structural tissue ( T = −2.10, p = 0.041) but were not significantly related to masses of any other body compartment or levels of circulating hormone levels.

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failed to reach significancep = 0.059so close (0.05 < p ≤ 0.1)

In the multiple regression analysis, level of restriction was a significant factor negatively influencing the levels of SOD ( T = −2.77, p = 0.008) and an effect of circulating IGF-1 marginally failed to reach significance ( T = −1.94, p = 0.059): overall least squares regression F 2,40 = 3.87, p = 0.029, r 2 = 0.162.

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