Quantification of the BLI signal 6 hours after heating revealed a highly significant increase in lucF expression in the heated tumor-bearing leg, in comparison to BLI signal measured before heating the left leg and that in the contra lateral non heated leg (Fig 3C , m +/− SD; n = 29, p < 0.01).
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Spatiotemporal control of gene expression in bone-marrow derived cells of the tumor microenvironment induced by MRI guided focused ultrasound.
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