Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.

PLoS One · 2015 · PMC4697807 · PMID 26720709

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a weak trendno p-value reported

In light of the precedence for GPR39 playing a role in GSIS [ 4 ], the effects on GSIS in INS-1E cells presented here, and a weak trend between DMR and INS-1E data in the presence of Zn 2+ (data not shown), glucose tolerance tests in vivo were conducted to further explore the role of GPR39 on GSIS.

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